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Platelet-Rich Plasma (PRP) Treatment in Fertility
In the past few years, there have been noticeable shifts in family planning trends as more and more women choose to postpone being parents, increasing their risk of developing insufficient ovarian function by the time they feel ready for pregnancy. This is because both the quantity and quality of eggs produced by females decrease with age. However, the ability to restore ovarian function safely is vital, which is when ovarian rejuvenation or ovarian PRP enters the picture. Ovarian rejuvenation is an added-on treatment that has been demonstrated to improve egg quality and the number of women with poor ovarian reserves. The procedure works by infusing platelet-rich plasma (PRP).
This page discusses all you need to know about platelet-rich plasma (PRP) for IVF.
What is Platelet-Rich Plasma (PRP) for IVF ?
PRP therapy is a procedure that uses the patient's own blood to stimulate the healing and regeneration of tissue. The procedure begins with drawing a small volume of blood from the individual's body, usually from the arm. This blood sample is subsequently separated into platelets and other blood components. Following isolation, the concentrated platelet-rich plasma is directly injected into the ovaries using a similar ultrasound-guided procedure used for retrieving an egg. It activates stem cells, increasing the number of viable eggs and one's chances of becoming pregnant. In certain circumstances, PRP might even help restore menstruation.
After administering PRP, the specialist will monitor the patient's hormonal levels, redo the ultrasound scan to ensure that the treatment is effective, and then calculate the optimal time for an IVF cycle.
Who should consider PRP fertility treatment ?
Egg quantity and quality can decrease with age, reducing the chance of conception for individuals who are in their thirties and forties. Some younger women are predisposed to premature failure of the ovaries, inadequate hormone levels, and unexplained infertility. Platelets, consisting of a growth factor that promotes healing, can help to address these challenges. Your fertility doctor may recommend PRP therapy as an option if:
- You are trying to get pregnant for about six months to one year without success.
- You have had multiple miscarriages.
- You have been identified as having secondary infertility.
- You experienced an unsuccessful IVF cycle because of the quality of the egg or
embryo.
To assess whether or not an individual is suitable for ovarian rejuvenation with PRP, fertility specialists may perform a blood test, an ultrasound, and a thorough evaluation of the patient's treatment history —all routine fertility testing procedures.
Who should consider PRP fertility treatment ?
PRP is typically done from the patient's own blood, but it can also be obtained from the blood of another person.
Step 01
The PRP procedure begins with a medical professional extracting a blood sample in the same way that tubes of blood are routinely collected.
Step 02
The blood is centrifuged (placed in a machine that spins rapidly, forcing the various blood components to separate) for approximately 15 minutes.
Step 03
A technician in the laboratory collects the plasma, which is now rich in platelets but free from cellular components, to prepare for injection.
Applications of Ovarian PRP in Fertility Treatment
PRP therapy can be used to address a variety of reproductive concerns, including:
Enhance Egg Quality
PRP injections can enhance the quality of IVF eggs. Injecting platelet-rich plasma (PRP) in the ovaries can increase the growth of healthy ovarian follicles, resulting in the generation of high-quality eggs.
Improves Embryo Implantation
Injecting PRP into the uterus increases the thickness as well as the quality of the uterine lining, providing a favourable environment for successful embryo implantation.
Combination with Additional Fertility Treatments:
Injections of PRP boost the health of the reproductive organs, increasing the probability of successful conception. This therapy is frequently used in conjunction with other fertility procedures, including IVF and IUI.
PRP Benefits in Fertility Treatment
Improved Ovarian Function:
PRP therapy improves the chances of successful ovulation and pregnancy.
Enhanced Pregnancy Rates
Research suggests that PRP therapy can improve the odds of pregnancy, even after failed IVF cycles.
Relatively Safe Procedure
PRP therapy is a safe and effective treatment that uses the patient's own blood to reduce the chance of adverse reactions or rejection.
Platelet-Rich Plasma (PRP) Process: Step-by-Step
Patient Assessment and Consultation
The procedure begins with a thorough review of the individual's medical history, present medical status, and any specific concerns about their condition. This evaluation helps the fertility professional in determining whether or not PRP therapy is a suitable treatment choice for the patient's specific needs.
Blood Collection
After deciding to go ahead with PRP therapy, an individual undergoes a blood sample collection procedure. Typically, a small quantity of blood is drawn through a vein, mostly from the arm, just like a usual blood test.
Blood Processing
The obtained blood is subsequently processed using a centrifuge. The centrifuge is a device that swirls the blood at extremely fast speeds, dividing it into its constituent parts based on density. This process usually takes around 10-15 minutes.
Platelet-Rich Plasma Separation
As the blood rotates in the centrifuge, heavy elements, such as white and red blood cells, separate from the lightweight plasma. The plasma layer, containing a greater number of platelets, is meticulously collected using sterile methods.
Platelet Activation (Optional)
In rare circumstances, the collected PRP might be further treated in order to activate the platelets before administration. Activation can be performed by a variety of methods, including the addition of thrombin or calcium chloride, which prompts the platelets to release growth factors.
Preparing for Application
Once the PRP has been collected and, if required, activated, it is ready for application to the targeted region-the ovaries.
PRP Application
The obtained PRP is subsequently given to the patient. However, it is not just an injection. A skilled IVF specialist performs the procedure under general anaesthesia or sedation. Using ultrasound guidance, the specialist injects the prepped PRP in the ovaries with surgical precision.
Monitoring & follow-up visits
Patients undergo periodic assessments after PRP therapy to evaluate their response to the treatment and make any required changes to their care plan. Further appointments are often scheduled to monitor progress and ensure the best results.
Monitoring & follow-up visits
Patients undergo periodic assessments after PRP therapy to evaluate their response to the treatment and make any required changes to their care plan. Further appointments are often scheduled to monitor progress and ensure the best results.
Platelet-Rich Plasma (PRP) Process: Step-by-Step
Intraovarian PRP Therapy is a safe method that includes administering plasma into the ovaries with similar equipment used to retrieve eggs during an IVF process.
PRP is made from the patient's own blood; thus, there is a low risk of undesirable reactions or consequences. However, like in any kind of medical procedure, minor risks may exist, like infection, bleeding, and or minor discomfort at the site of the injection.
Despite the potential advantages listed above, it is important to note that this is a new treatment approach and is currently being researched.
If you are considering using intraovarian PRP therapy as a fertility treatment, you should talk to a trained fertility doctor about the risks and advantages.
Future of PRP in Fertility Treatment
In the context of fertility treatments, ovarian rejuvenation using PRP shows promise for the future. As technology advances, PRP therapy's effectiveness in boosting fertility is expected to improve. Continuous research and clinical studies aim to improve this treatment, which could lead to better outcomes for people experiencing infertility. PRP therapy is remarkable for its safe and natural approach, which uses the body's own blood to improve ovarian function.
For those thinking about fertility enhancement options, PRP therapy could be a potential option to consider. Staying informed on improvements in PRP may provide hope and opportunities for people on their path to parenthood.
Why Choose Nova IVF for PRP Fertility Treatment?
Nova IVF is a premier fertility centre renowned for its experience and expertise in fertility treatments, particularly modern therapies such as PRP therapy. Our team of professionals is committed to offering personalised care, tailoring every patient's treatment plan to their specific reproductive needs. Nova IVF, with its cutting-edge facilities and equipment, provides a supportive atmosphere for all fertility procedures. Our commitment to quality is shown in our excellent success rates, making us a reliable choice for people seeking effective fertility treatments.
